Using Blood Pressure-Lowering Treatment In Very Elderly Shows Significant Reductions In Mortality

June 20th, 2008 by poster

Lowering the blood pressure of elderly patients could cut their total mortality by a fifth and their rate of cardiovascular events by a third, according to a new study presented at the American College of Cardiology in Chicago and published simultaneously in the New England Journal of Medicine.
The 3,845 patient Hypertension in the Very Elderly Trial (HYVET), which is coordinated by scientists from Imperial College London, is the largest ever clinical trial to look at the effects of lowering blood pressure solely in those aged 80 and over. Buy propecia without prescription Patients were given either a placebo or the diuretic indapamide slow release (SR) 1.5mg, with the addition of the ACE inhibitor perindopril in tablet form once a day.
The research shows that the benefits of treatment include a 21% (p=0.02) reduction in total mortality rate, a 39% (p=0.05) reduction in stroke mortality rate, a 64% (pgeneric levitra online buy | Buy acomplia without prescription | Buy diflucan pills

Cook Medical Launches Online Destination To Educate Physicians And Patients On A Leading Form Of Erectile Dysfunction

June 18th, 2008 by poster

Cook Medical , announced the launch of www.MensHealthPD.com, an informational microsite dedicated to educating physicians, men and their partners about the symptoms, treatment options and latest research on Peyronie’s disease, a common form of erectile dysfunction thought to affect more than 80, 000 men in the UK, with one study suggesting 1% of the male population may suffer. MensHealthPD.com is designed to provide the latest information on the painful ailment and also offers medical professionals, patients and their partners public and physician forums for discussing the disease, posting questions and sharing personal experiences about the condition.
For many men and their partners, erectile dysfunctions, such as Peyronie’s disease, are embarrassing and uncomfortable to discuss. It is also often difficult to find a centralised repository on the web with the helpful information needed to obtain answers on these conditions. MensHealthPD.com is changing all this by offering these individuals a one-stop, discreet Peyronie’s resource armed with the following assets:
- Video answers to the most commonly asked questions about Peyronie’s disease provided by some the world’s leading Peyronie’s doctor experts.
- A Q&A forum where patients, partners and doctors can discuss available Peyronie’s treatments, exchange ideas on coping with the disease and more.
- Details of the signs, symptoms and progression of Peyronie’s disease.
- A helpful list of questions to prepare a man afflicted with Peyronie’s for his first doctor’s visit
Many men living with Peyronie’s disease go untreated because so few GPs understand the disease. In fact, a recent study showed that over half of primary care physicians were unsure any effective treatments for the disease existed. Therefore, many men never get referred to a urologist who may be able to treat the condition.
Buy diflucan pills MensHealthPD.com will serve as a single source where GPs, urologists and other physicians from around the world can access the latest peer-reviewed research on Peyronie’s treatment options as well as other relevant published scientific data. The following resources are available on the microsite to educate these doctors on the wide array of treatment options available for Peyronie’s sufferers:
- A summary of current surgical and non-surgical treatment options with links to the most current published research.
- The latest peer-reviewed research on Peyronie’s disease posted in the MEDLINE database of citations and abstracts and indexed through PubMed, offered by the US National Library of Medicine and the National Institutes of Health (NIH).
- A secure, physicians-only Q&A forum where doctors can share best practices and increase their collective knowledge with their colleagues.
Raj Persad, a Consultant Urologist at United Bristol Healthcare NHS explains: "This is a distressing disease with huge potential psychosexual impact. In an area such as this where treatment options for different stages of the disease are limited and often confusing for patients we need to share as much information as possible about new management options. This website will benefit both clinicians and patients alike in enabling the sharing of experience and information which could be of benefit to all’
About Peyronie’s Disease
Peyronie’s disease, also known as penile curvature, is estimated to affect nearly four out of every 100 males between the ages 45 and 65[3]. The disease is linked to erectile dysfunction in 20 to 40 percent of the sufferers and is characterised by the formation of a plaque or hardened scar tissue beneath the skin of a man’s penis. The scarring is non-cancerous and may lead to a painful erection and curvature of the penis during erection.

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Biovail Receives FDA Approval For Aplenzin (BVF-033) For The Treatment Of Depression

June 18th, 2008 by poster

Biovail Corporation (NYSE: BVF) (TSX: BVF) announced that it has received Approval from the United States Food and Drug Administration (FDA) for its New Drug Application (NDA) for Aplenzin™ (formerly known as BVF-033), a once-daily formulation of bupropion hydrobromide developed by Biovail for the treatment of depression in adults.
Buy zithromax without prescription Aplenzin™ is an alcohol-resistant formulation of a new bupropion salt and has been approved in 174mg, 348mg, and 522mg extended-release tablets. The 522mg dosage strength provides patients requiring the maximum allowable dose of bupropion the only single tablet, once-daily option.
Biovail remains in active partnership discussions for the commercialization rights for Aplenzin™ in the United States.
About Biovail Corporation
Biovail Corporation is a specialty pharmaceutical company, engaged in the formulation, clinical testing, registration, manufacture, and commercialization of pharmaceutical products utilizing advanced drug-delivery technologies.
Biovail Corporation
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Federal Authorities Seize More Than 100,000 Dollars Of Unapproved Drugs Marketed As “Natural Supplements”

June 18th, 2008 by poster

At the request of the U.S. Food and Drug Administration, U.S. Marshals seized more than 14,000 dosage units of Shangai Regular, Shangai Ultra, Super Shangai, Natural?« Super Plus, and Lady Shangai. Although labeled as natural supplements, the seized products were all marketed to treat erectile dysfunction (ED), impotency, and/or to provide sexual enhancement, which caused them to be drugs under the Federal Food, Drug, and Cosmetic Act.
The seized products, valued at more than $100,000, contain undeclared active ingredients found in FDA-approved prescription drugs for ED, or similar substances. Use of these products may result in serious side effects and may interact in dangerous ways with medications that a consumer may already be taking.
"The FDA will not tolerate companies marketing unapproved drugs — products that have not proven to be safe or effective — as dietary supplements," said Margaret O’K. Glavin, associate commissioner for regulatory affairs. "The agency will pursue necessary legal action to make sure companies and their executives manufacture and distribute safe drug products."
The seized products, which originated in China, are packaged and distributed by Shangai Distributors, Inc. of Coamo, Puerto Rico. Buy generic ultram Although the products’ labels state they are natural supplements, these products are drugs and their sale is illegal without FDA approval. Before a new drug product may be legally marketed, it must be shown to be safe and effective.
In response to a consumer complaint, the FDA conducted an inspection of Shangai Distributors Inc., in November 2007. The FDA’s investigation and testing revealed that the seized products contained active drug ingredients found in FDA-approved ED prescription drugs and/or a substance with a structure similar to such drugs that may cause similar side effects and drug interactions. None of the drug ingredients are listed on the labels of any of the seized products.
The undeclared ingredients in these products may interact with nitrates found in some prescription drugs (such as nitroglycerin) and can lower blood pressure to dangerous levels. Consumers with diabetes, high blood pressure, high cholesterol, or heart disease often take nitrates. ED is a common problem in men with these medical conditions. Because they may have been advised against taking ED drugs, they may seek out products like these because they are marketed as "all natural" or as not containing the active ingredients in approved, prescribed ED drugs. Additionally, because the manufacturing source of the active ingredients in these products is unknown, consumers should be aware that the safety, efficacy, and purity of these ingredients can not be validated.
Despite being advised of the findings and the potential adverse health risk posed by the seized products and that regulatory action was possible, the company did not take any action to correct the violations. The FDA issued a press release on December 28, 2007 advising consumers not to buy or use the products. Prior to the seizure, the Puerto Rico Department of Health embargoed the seized products to protect the citizens of Puerto Rico and to support the FDA’s enforcement actions.
The FDA advises consumers who have used any of these products to discontinue use and consult their health care providers if they have experienced any adverse events that they believe are related to the use of these products. Consumers and health care professionals can report adverse events to FDA’s MedWatch program at 800-FDA-1088 or online at FDA recommends that consumers talk to their health care provider about FDA-approved treatments for erectile dysfunction. FDA may take further regulatory actions to protect consumers from these illegal products.
The complaint was filed by Assistant U.S. Attorney Jose M. Pizarro, deputy chief, Civil Division, United States Attorney’s Office, District of Puerto Rico.

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What Is Life Like For Teens With Allergies?

June 18th, 2008 by poster

A study into teenagers with food allergies will investigate what life is like for them in an attempt to improve their quality of life and curb the number of allergy-related deaths.
Scientists at the University of Portsmouth have created a quality of life questionnaire which asks teenagers what it is like for them to live with a food allergy. They are inviting young people with food allergies to come forward to take part in the study.
A previous UK study which examined all deaths from food-related allergies between 1992-2001 suggested that 35 per cent of deaths occurred in youngsters aged from 10-19.
Children aged 10-14 years accounted for 10 per cent of food allergy deaths and those aged 15-19 accounted for 25 per cent.
Heather Mackenzie, from the University’s School of Health Sciences and Social Work said:
"Although deaths from food allergy are rare, teenagers are overrepresented in these figures. This indicates that they find food allergies the most difficult to deal with."
In order to develop a draft questionnaire she has interviewed youngsters and discovered that their attitudes to food allergies vary and that the severity of the condition doesn’t always dictate the way they feel about it and the way they manage it. She said:
"Some teenagers have relatively mild food hypersensitivity but it has a drastic affect on their quality of life, and vice versa. Teenagers are especially vulnerable because they are learning to take responsibility for their food allergy, which is challenging in itself, whilst also trying to be a normal teenager. Those with serious allergies carry around pre-loaded injection kits containing adrenaline and some see it as a nuisance but it’s vital that they understand that it can save their lives and that thousands of others are in the same boat."
The aim of the new study is to provide doctors and other healthcare professionals with a tool to assess teenagers’ quality of life by finding out how they feel about their allergy. It will help doctors give them advice on how to manage their allergy and sources of further help.
Mackenzie says she wants more volunteers to complete the questionnaire in order to ensure that it accurately reflects teenagers’ concerns. Buy cipro pills She wants to hear from teenagers who would like to help people to understand more about what living with a food allergy is like for them.
The Anaphylaxis Campaign, a national charity for people with potentially life-threatening allergies (www.anaphylaxis.org.uk), will be helping the study by sending questionnaires to some of its teenage members.
David Reading, director of the Anaphylaxis Campaign, said: "Food allergy can occasionally be serious, but we are convinced that teenagers who are affected can learn how to protect themselves. We would hope that this study will lead to a greater understanding of the problem that allergic teenagers face and better medical advice for them."
Young people aged 13-18 who would like to take part can go to www.port.ac.uk/foodallergysurvey or contact Heather Mackenzie on 023 9284 4441 or heather.mackenzie@port.ac.uk. They will be asked to complete a short questionnaire about how having food allergies affects their life and will be entered into a prize draw to win an iPod.
For more information visit the following
link.
Food allergies affect approximately 2.3% of teenagers and approximately 1.4-1.8% of the UK adult population as a whole
The most common allergies are to peanuts and other nuts and they frequently severe but other foods which can be triggers include egg, milk, fish, shellfish, soya, sesame and wheat.
Any allergic reaction, including the most extreme form, anaphylactic shock, occurs because the body’s immune system reacts inappropriately in response to the presence of a substance that it wrongly perceives as a threat.
From 1992 - 2002 the UK the youngest person to die from a fatal reaction to peanut was 13 years old and the median age was 21 years.
6 children aged between 10-14 years died in the years between 1992-2001 in the UK and 15 teenagers aged 15-19 years died (25%).
Symptoms of food related allergies include
- generalised flushing of the skin
- nettle rash (hives) anywhere on the body
- abdominal pain, nausea and vomiting
- swollen lips
- anaphylaxis
- sense of impending doom
- swelling of throat and mouth
- difficulty in swallowing or speaking
- alterations in heart rate
- severe asthma
- sudden feeling of weakness (drop in blood pressure)
- collapse and unconsciousness
University of Portsmouth

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